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Wnt-reactive alveolar epithelial progenitor cells (AEP) in AT2 are a stable lineage during alveolar homeostasis, but rapidly expand to regenerate most of the alveolar epithelium after acute lung injury, showing stronger stemness

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Karin M, Gallagher E

More recently, SUSTAIN-CSX (n = 1,416, cardiac surgery patients) showed no improvement in postoperative organ dysfunction or mortality with high-dose IV sodium selenite (Stoppe et al., 2023)

Appears to modulate gene expression related to vascularization and nitric oxide signaling, suggesting potential benefits for blood flow and antioxidant activity8

Insulin-like growth factor I and growth hormone (GH) treatment in GH-deficient humans: differential effects on protein, glucose, lipid, and calcium metabolism